PREX2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPREX2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration0.65 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionAffinity Purified PtdIns(3, 4, 5)-dependent Rac exchanger 2a Antibody. Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
ImmunogenImmunogen: Synthetic peptide taken within amino acid region 720-900 on PREX2 protein. Expression: Isoform 1 is highly expressed in skeletal muscle, heart and placenta, absent from peripheral blood leukocytes. Isoform 2 is expressed in skeletal muscle, kidney, small intestine, and placenta. Isoform 3 is expressed in the heart.
Other Names[4; 5)-dependent Rac exchanger 2; 5-trisphosphate-dependent Rac exchanger 2 protein; DEP domain-containing protein 2; DEP.2; Phosphatidylinositol 3; PtdIns(3, 4, 5)-dependent Rac exchanger 2], [PREX2; DEPDC2; P-Rex2; PtdIns(3,4,5)-dependent Rac exchanger 2]
Gene, Accession #[PREX2], NCBI: DAA05334.1, UniProt: Q70Z35
Catalog #MBS540890
Price$390
Order / More InfoPREX2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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