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Antigenic Specificity | PREX2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 0.65 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified PtdIns(3, 4, 5)-dependent Rac exchanger 2a Antibody. Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 720-900 on PREX2 protein. Expression: Isoform 1 is highly expressed in skeletal muscle, heart and placenta, absent from peripheral blood leukocytes. Isoform 2 is expressed in skeletal muscle, kidney, small intestine, and placenta. Isoform 3 is expressed in the heart. |
Other Names | [4; 5)-dependent Rac exchanger 2; 5-trisphosphate-dependent Rac exchanger 2 protein; DEP domain-containing protein 2; DEP.2; Phosphatidylinositol 3; PtdIns(3, 4, 5)-dependent Rac exchanger 2], [PREX2; DEPDC2; P-Rex2; PtdIns(3,4,5)-dependent Rac exchanger 2] |
Gene, Accession # | [PREX2], NCBI: DAA05334.1, UniProt: Q70Z35 |
Catalog # | MBS540890 |
Price | $390 |
Order / More Info | PREX2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |