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Antigenic Specificity | Phospho-AMPKbeta1-S108 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular locali |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding S108 of human AMPKbeta1 Calculated MW: 30kDa Observed MW: 40kDa |
Other Names | [Phospho-AMPKb1-S108, AMPK; HAMPKb] |
Gene, Accession # | [PRKAB1], Gene ID: 5564, NCBI: Q9Y478.4, UniProt: Q9Y478 |
Catalog # | MBS9126886 |
Price | $235, $350, $525 |
Order / More Info | Phospho-AMPKbeta1-S108 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |