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Antigenic Specificity | CREBBP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA; acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902). |
Immunogen | Immunogen: Recombinant Human CREB-binding protein (2217-2442AA) |
Other Names | [CREB-binding protein; CREBBP; CBP] |
Gene, Accession # | [CREBBP], Gene ID: 1387, NCBI: NP_001073315.1, UniProt: Q92793 |
Catalog # | MBS7104641 |
Price | $160, $235 |
Order / More Info | CREBBP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |