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Antigenic Specificity | GABA Receptor 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes ~100 kDa of GABA Receptor 1 Protein. It is cross react to human and rat. The other species are not tested. Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. It acts at GABA receptors to produce fast synaptic inhibitory signals. The GABA (B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA (B) receptor 1 and GABA (B) receptor 2. The overexpression of one particular gene encoding for G-protein-activated inward rectifying potassium type 2 (GIRK2) channel subunit and its coupling to GABA (B) receptors may contribute to a range of mental and functional disabilities |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Gene ID: 5970 |
Catalog # | MBS460152 |
Price | $285 |
Order / More Info | GABA Receptor 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Grifa, A., Totaro, A., Rommens, J.M., Carella, M., Roetto, A., Borgato, L., Zelante, L. and Gasparini, P (1998). GABA (gamma-amino-butyric acid) neurotransmission: identification and fine mapping of the human GABAB receptor gene. Biochem. Biophys. Res. Commun. 250 (2), 240-245. |