TXN Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTXN
Clone[1850CT339.14.1]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1,k
FormatProtein G purified
Size0.05 mL, 0.2 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis antibody is generated from a mouse immunized with a recombinant protein from human. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
Immunogenn/a
Other Names[Purified Mouse (Mab); Thioredoxin; Trx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP; TXN; TRDX; TRX; TRX1]
Gene, Accession #[TXN], Gene ID: 7295, NCBI: NP_001231867.1, UniProt: P10599
Catalog #MBS9231280
Price$165, $370
Order / More InfoTXN Antibody from MYBIOSOURCE INC.
Product Specific ReferencesWollman E.E.,et al.J. Biol. Chem. 263:15506-15512(1988). Tagaya Y.,et al.EMBO J. 8:757-764(1989). Tonissen K.F.,et al.Gene 102:221-228(1991). Reddy P.G.,et al. Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases. Liu A.,et al. Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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