SIN3B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySIN3B
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF)
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DescriptionThe antibody detects endogenous levels of total SIN3B protein. Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription By similarity.Ishikawa K., DNA Res. 5:169-176(1998).The MGC Project Team, Genome Res. 14:2121-2127(2004).Wysocka J., Genes Dev. 17:896-911(2003).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human SIN3B.
Other Names[Paired amphipathic helix protein Sin3b; Transcriptional corepressor Sin3b; Histone deacetylase complex subunit Sin3b; SIN3B; KIAA0700]
Gene, Accession #[SIN3B], Gene ID: 23309, NCBI: NP_001284524.1, UniProt: O75182
Catalog #MBS9412738
Price$200, $255
Order / More InfoSIN3B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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