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Antigenic Specificity | SIN3B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total SIN3B protein. Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription By similarity.Ishikawa K., DNA Res. 5:169-176(1998).The MGC Project Team, Genome Res. 14:2121-2127(2004).Wysocka J., Genes Dev. 17:896-911(2003). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human SIN3B. |
Other Names | [Paired amphipathic helix protein Sin3b; Transcriptional corepressor Sin3b; Histone deacetylase complex subunit Sin3b; SIN3B; KIAA0700] |
Gene, Accession # | [SIN3B], Gene ID: 23309, NCBI: NP_001284524.1, UniProt: O75182 |
Catalog # | MBS9412738 |
Price | $200, $255 |
Order / More Info | SIN3B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |