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Antigenic Specificity | POLR3A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.89 mg/ml |
Applications | Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition. |
Immunogen | Immunogen: POLR3A antibody was raised in rabbit using a recombinant fragment corresponding to a region within amino acids 182 and 482 of POLR3A |
Other Names | [Affinity Purified Rabbit POLR3A; POLR3A; POLR3A; hRPC155; RNA polymerase III subunit RPC155-D; POLRA-3; POLRA 3; POLR3A; RNA polymerase III subunit C160; POLRA 3; RPC155; DNA-directed RNA polymerase III subunit RPC1; POLR3A; RPC1; POLRA-3; DNA-directed RNA polymerase III subunit A] |
Gene, Accession # | [POLR3A], Gene ID: 11128 |
Catalog # | MBS5312060 |
Price | $485 |
Order / More Info | POLR3A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |