c-Abl Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-c-Abl antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | c-Abl |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The c-Abl proto-oncogene encodes a nonreceptor protein tyrosine kinase that is ubiquitously expressed and highly conserved in metazoan evolution. c-Abl protein is distributed in both the nucleus and the cytoplasm of cells. It is implicated in regulating cell proliferation, differentiation, apoptosis, cell adhesion and stress responses (1-3). c-Abl kinase activity is increased in vivo by diverse physiological stimuli including integrin activation, PDGF stimulation and binding to c-Jun, Nck and RFX1 (2, 4). The in vivo mechanism of regulation of c-Abl kinase activity is not completely understood. Tyr245 is located in the linker region between the SH2 and catalytic domains. This positioning is conserved among Abl family members. Phosphorylatio |
| Immunogen | Immunogen: C term-peptide of human ABL1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [ABL1; ABL; JTK7; bcr/abl; c-ABL; p150; v-abl] |
| Gene, Accession # | [c-Abl], Gene ID: 25, NCBI: NP_005148.2, UniProt: P00519 |
| Catalog # | MBS8504779 |
| Price | $310 |
| Order / More Info | c-Abl Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Wang, J.Y. et al. (2000) Oncogene 19, 5643-5650. 2. Van Etten, R.A. et al. (1999) Trends Cell. Biol. 9, 179-182. 3. Danial, N.N. et al. (2000) Oncogene 19, 2523-2531. 4. Shaul, Y. et al. (2000) Cell Death Differ. 7, 10-16. 5. Brasher, B.B. et al. (2000) J. Biol. Chem. 275, 35631-35637. 6. Pluk, H. et al. (2002) Cell 108, 247-259. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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