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Antigenic Specificity | Human CD41 |
Clone | [PM6/248] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | no preservative |
Size | 1 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human CD41 antibody, clone PM6/248 recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone PM6/248 recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex. |
Immunogen | Immunogen: Human platelet plasma membrane Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Human |
Other Names | [integrin alpha-IIb preproprotein; Integrin alpha-IIb; integrin alpha-IIb; GPalpha IIb; platelet fibrinogen receptor, alpha subunit; platelet membrane glycoprotein IIb; platelet-specific antigen BAK; protein phosphatase 1, regulatory subunit 93; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD_antigen: CD41Cleaved into the following 3 chains:Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2], [ITGA2B; ITGA2B; GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2; BDPLT16; PPP1R93; GP2B; ITGAB; GPIIb] |
Gene, Accession # | [CD41], Gene ID: 3674, NCBI: NP_000410.2, UniProt: P08514 |
Catalog # | MBS210248 |
Price | $675 |
Order / More Info | Human CD41 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |