FGFR4 (N-term) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FGFR4 (N-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This FGFR4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 143-178 amino acids from the N-terminal region of human FGFR4. Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the product |
| Immunogen | n/a |
| Other Names | [Fibroblast growth factor receptor 4; FGFR-4; CD334; FGFR4; JTK2; TKF] |
| Gene, Accession # | [FGFR4], Gene ID: 2264, NCBI: NP_001278909.1, UniProt: P22455 |
| Catalog # | MBS9212481 |
| Price | $165, $370 |
| Order / More Info | FGFR4 (N-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Partanen J.M.,et al.EMBO J. 10:1347-1354(1991). Ron D.,et al.J. Biol. Chem. 268:5388-5394(1993). Takaishi S.,et al.Biochem. Biophys. Res. Commun. 267:658-662(2000). Kostrzewa M.,et al.Mamm. Genome 9:131-135(1998). Ezzat S.,et al.J. Clin. Invest. 109:69-78(2002). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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