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Antigenic Specificity | CASP9 (S196) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.42 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CASP9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S196 of human CASP9. Caspase 9 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. |
Immunogen | n/a |
Other Names | [Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6; Caspase-9 subunit p35; Caspase-9 subunit p10; CASP9; MCH6] |
Gene, Accession # | [CASP9], Gene ID: 842, NCBI: NP_001220.2, UniProt: P55211 |
Catalog # | MBS9207453 |
Price | $165, $370 |
Order / More Info | CASP9 (S196) Antibody from MYBIOSOURCE INC. |
Product Specific References | Martin, M.C., et al., J. Biol. Chem. 280(15):15449-15455 (2005). Raina, D., et al., J. Biol. Chem. 280(12):11147-11151 (2005). Cornelis, S., et al., Oncogene 24(9):1552-1562 (2005). Mohammad, R.M., et al., Mol. Cancer Ther. 4(1):13-21 (2005). Tacconi, S., et al., Exp. Neurol. 190(1):254-262 (2004). |