NKX2.2 (Neuroendocrine & Ewing Sarcoma Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNKX2.2 (Neuroendocrine & Ewing Sarcoma Marker)
Clone[SPM564]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, chicken
IsotypeIgG2b, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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DescriptionSpecificity: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing'sarcoma, and was shown to be differentially upregulated in Ewing'sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing'sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
ImmunogenImmunogen: Human NKX2.2 recombinant protein
Other Names[Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman], [NKX2-2; NKX2-2; NKX2B; NKX2.2; NKX2.2; NKX2B]
Gene, Accession #[NKX2-2], Gene ID: 4821, NCBI: NP_002500.1, UniProt: O95096
Catalog #MBS438359
Price$190, $340, $340
Order / More InfoNKX2.2 (Neuroendocrine & Ewing Sarcoma Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesWang, Y.C. et al. (2009) Endocr Relat Cancer 16, 267-79. Yoshida A et. al. Am J Surg Pathol. 2012;36(7):993-9
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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