AXIN2 (C-term), 816-843 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | AXIN2 (C-term), 816-843 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, rat) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This AXIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 816-843 amino acids from the C-terminal region of human AXIN2. The Axin-related protein, Axin2, presumably plays animportant role in the regulation of the stability of beta-cateninin the Wnt signaling pathway, like its rodent homologs, mouseconductin/rat axil. In mouse, conductin organizes a multiproteincomplex of APC (adenomatous polyposis of the colon), beta-catenin,glycogen synthase kinase 3-beta, and conductin, which leads to thedegradation of beta-catenin. Apparently, the deregulation ofbeta-catenin is an important event in the genesis of a number ofmalignancies. The AXIN2 gene has been mapped to 17q23 |
| Immunogen | n/a |
| Other Names | [Axin-2; Axin-like protein; Axil; Axis inhibition protein 2; Conductin; AXIN2] |
| Gene, Accession # | [AXIN2], Gene ID: 8313, NCBI: NP_004646.3, UniProt: Q9Y2T1 |
| Catalog # | MBS9210236 |
| Price | $165, $370 |
| Order / More Info | AXIN2 (C-term), 816-843 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Inkster, B., et al. Neuroimage (2010) In press : Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010) Couch, F.J., et al. Cancer Epidemiol. Biomarkers Prev. 19(1):251-257(2010) Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009) Olschwang, S., et al. J Oncol 2009, 306786 (2009) : Dong, X., et al. Cytogenet. Cell Genet. 93 (1-2), 26-28 (2001) : Liu, W., et al. Nat. Genet. 26(2):146-147(2000) von Kries, J.P., et al. Nat. Struct. Biol. 7(9):800-807(2000) Kikuchi, A. Cytokine Growth Factor Rev. 10 (3-4), 255-265 (1999) : Mai, M., et al. Genomics 55(3):341-344(1999) |
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MYBIOSOURCE INC.
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