Edit |   |
---|---|
Antigenic Specificity | PAK2 |
Clone | [7H3-E2-F5] |
Host Species | Mouse |
Reactive Species | human, monkey |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene. |
Immunogen | Immunogen: Purified recombinant fragment of PAK2 expressed in E. Coli. |
Other Names | [PAK65; PAKgamma] |
Gene, Accession # | [PAK2], Gene ID: 5062, NCBI: NP_002568.2, UniProt: Q13177 |
Catalog # | MBS8538540 |
Price | $280 |
Order / More Info | PAK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |