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Antigenic Specificity | CHRNB4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CHRNB4 antibody detects endogenous levels of total CHRNB4. Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.Subunit Structure: Neuronal AChR is composed of two different types of subunits: alpha and beta. Beta-4 subunit can be combined to alpha-2, alpha-3 or alpha-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly (PubMed:16120769). Interacts with LYPD6 (PubMed:27344019). The pentamer alpha3-beta-4 interacts with the conotoxin BuIA (By similarity). The heteropentamer composed of alpha-3 and beta-4 subunits interacts w |
Immunogen | Immunogen: A synthesized peptide derived from human CHRNB4 Subcellular Location: Cell Junction > Synapse > Postsynaptic Cell Membrane. Cell Membrane. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%) |
Other Names | [acetylcholine receptor, nicotinic, beta 4 (neuronal); ACHB4_HUMAN; AChR; Cholinergic receptor nicotinic beta 4; Cholinergic receptor nicotinic beta polypeptide 4; cholinergic receptor, nicotinic, beta polypeptide 4; Chrnb4; Neuronal acetylcholine receptor subunit beta-4; Neuronal nicotinic receptor beta 4 subunit] |
Gene, Accession # | [CHRNB4], Gene ID: 1143, NCBI: NP_000741.1, UniProt: P30926 |
Catalog # | MBS9610015 |
Price | $240, $280 |
Order / More Info | CHRNB4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |