CHRNB4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCHRNB4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: CHRNB4 antibody detects endogenous levels of total CHRNB4. Function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.Subunit Structure: Neuronal AChR is composed of two different types of subunits: alpha and beta. Beta-4 subunit can be combined to alpha-2, alpha-3 or alpha-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly (PubMed:16120769). Interacts with LYPD6 (PubMed:27344019). The pentamer alpha3-beta-4 interacts with the conotoxin BuIA (By similarity). The heteropentamer composed of alpha-3 and beta-4 subunits interacts w
ImmunogenImmunogen: A synthesized peptide derived from human CHRNB4 Subcellular Location: Cell Junction > Synapse > Postsynaptic Cell Membrane. Cell Membrane. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%)
Other Names[acetylcholine receptor, nicotinic, beta 4 (neuronal); ACHB4_HUMAN; AChR; Cholinergic receptor nicotinic beta 4; Cholinergic receptor nicotinic beta polypeptide 4; cholinergic receptor, nicotinic, beta polypeptide 4; Chrnb4; Neuronal acetylcholine receptor subunit beta-4; Neuronal nicotinic receptor beta 4 subunit]
Gene, Accession #[CHRNB4], Gene ID: 1143, NCBI: NP_000741.1, UniProt: P30926
Catalog #MBS9610015
Price$240, $280
Order / More InfoCHRNB4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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