Edit |   |
Antigenic Specificity | Human PlGF-2 |
Clone | [IgG1; 3B10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Placenta growth factor (PlGF) is a member of the PDGF/VEGF family of growth factors that share a conserved pattern of eight cysteines. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF1), 152 (PlGF2), and 203 (PlGF3) amino acids (aa) respectively. Only PlGF2 contains a highly basic heparinbinding 21 aa insert at the C-terminus. In the mouse, only one P lGF that is the equivalent of human PlGF2 has been identified. Human PlGF1 shares 56%, 55%, 74% and 95% aa identity with the appropriate isoform of mouse, rat, canine and equine PlGF. PlGF is mainly found as variably glycosylated, secreted, 55 - 60 kDa disulfide linked homodimers. Mammalian cells expressing PlGF include villous trophoblasts, decidual ce |
Immunogen | Immunogen: Recombinant human PlGF-2 (RT #300-019) |
Other Names | [human PlGF-2 (#3B10); Placenta growth factor; PlGF], [PGF; PGF; PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760; PGFL; PLGF; PlGF] |
Gene, Accession # | [PlGF-2], Gene ID: 5228, NCBI: NP_001193941.1, UniProt: P49763 |
Catalog # | MBS690323 |
Price | $365 |
Order / More Info | Human PlGF-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. DiPalma, T. et al. (1996) Mamm. Genome 7:6. 2. Cao, Y. et al. (1997) Biochem. Biophys. Res. Commun. 235:493. 3. Ferrara, N. et al. (1997) Endocrin. Rev. 18:4 4. Kim KJ et al, Exp Mol Med 44:10-9, 2012 5. De Falco S, Exp Mol Med 44:1-9, 2012 |