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Antigenic Specificity | Interleukin 1 receptor-like 1, IL1RL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interleukin 1 receptor-like 1, also known as IL1RL1 and ST2, is a member of the Toll-like receptor superfamily. [1]The ST2 protein has two isoforms and is directly implicated in the progression of cardiac disease: a soluble form (referred to as soluble ST2 or sST2) and a membrane-bound receptor form (referred to as the ST2 receptor or ST2L). ST2 gene expression is related to the growth of cells and that an unknown signal is transduced to control cell proliferation by binding of specific ligand(s).[2] Mutations in this gene have been linked to atopic dermatitis and asthma. |
Immunogen | Immunogen: A synthetic peptide (conjugated with KLH) corresponding to the extracellular region of mouse IL1RL1. |
Other Names | [Interleukin 1 receptor-like 1; IL1RL1], [IL1RL1; IL1RL1; T1; ST2; DER4; ST2L; ST2V; FIT-1; IL33R; DER4; ST2; T1] |
Gene, Accession # | [IL1RL1], Gene ID: 9173, NCBI: NP_003847.2, UniProt: Q01638 |
Catalog # | MBS355072 |
Price | $275 |
Order / More Info | Interleukin 1 receptor-like 1, IL1RL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Brint EK, Xu D, Liu H, Dunne A, McKenzie AN, O'Neill LA, Liew FY (April 2004). ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat. Immunol. 5 (4): 373-9. 2. Tominaga, S. A putative protein of a growth specific cDNA from BALB/c-3T3 cells is highly similar to the extracellular portion of mouse interleukin 1 receptor. FEBS Lett. 258: 301-304, 1989 |