Smad2 (Ab-465) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Smad2 (Ab-465) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total Smad2 protein. Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.Riggins G.J., Nat. Genet. 13:347-349(1996). Zhang Y., Nature 383:168-172(1996). Eppert K., Cell 86:543-552(1996). |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human Smad2. |
| Other Names | [JV18-1; Mad-related protein 2; MADH2; MADR2; Mothers against decapentaplegic homolog 2] |
| Gene, Accession # | [Smad2], Gene ID: 4087, NCBI: NP_001003652.1, UniProt: Q15796 |
| Catalog # | MBS9413543 |
| Price | $200, $255 |
| Order / More Info | Smad2 (Ab-465) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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