B-Catenin Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | B-Catenin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Frozen |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Purified polyclonal CTNNB1 antibody specific for Human CTNNB1 for use in Immunohistochemistry and Western blot. Description: CTNNB1 is composed of 781 amino acids with a molecular weight of 85497 Da. There are 12 ARM repeats between positions 151 and 666.Biological Significance: CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the p |
| Immunogen | Immunogen: B-Catenin antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human Catenin beta, identical to the related rat and Rabbit sequence as the immunogen. Post-Translational Modifications: Phosphorylation at Ser-552 by AMPK promotes stabilizion of the protein, enhancing TCF/LEF-mediated transcription. Phosphorylated by NEK2. EGF stimulates tyrosine phosphorylation. Phosphorylation on Tyr-654 decreases CDH1 binding and enhances TBP binding |
| Other Names | [Affinity Purified Rabbit B-Catenin; B-Catenin; B-Catenin; Catenin beta; Beta Catenin; Catenin] |
| Gene, Accession # | Gene ID: 30265 |
| Catalog # | MBS5312614 |
| Price | $375 |
| Order / More Info | B-Catenin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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