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Antigenic Specificity | UBE2L3 (C-term), 106-135 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat (predicted reactivity: bovine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This UBE2L3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the C-terminal region of human UBE2L3. The modification of proteins with ubiquitin is animportant cellular mechanism for targeting abnormal or short-livedproteins for degradation. Ubiquitination involves at least threeclasses of enzymes: ubiquitin-activating enzymes (E1s),ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases(E3s). This gene encodes a member of the E2 ubiquitin-conjugatingenzyme family. This enzyme is demonstrated to participate in theubiquitination of p53, c-Fos, and the NF-kB precursor p105 invitro. Several alternatively spliced transcript variants hav |
Immunogen | n/a |
Other Names | [Ubiquitin-conjugating enzyme E2 L3; L-UBC; UbcH7; Ubiquitin carrier protein L3; Ubiquitin-conjugating enzyme E2-F1; Ubiquitin-protein ligase L3; UBE2L3; UBCE7; UBCH7] |
Gene, Accession # | [UBE2L3], Gene ID: 7332, NCBI: NP_001243284.1, UniProt: P68036 |
Catalog # | MBS9205020 |
Price | $165, $370 |
Order / More Info | UBE2L3 (C-term), 106-135 Antibody from MYBIOSOURCE INC. |
Product Specific References | Fransen, K., et al. Hum. Mol. Genet. 19(17):3482-3488(2010) Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010) Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010) Purbeck, C., et al. Biochemistry 49(7):1361-1363(2010) Han, J.W., et al. Nat. Genet. 41(11):1234-1237(2009) |