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Antigenic Specificity | VAV1 (pTyr174) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (expected from sequence), rat (expected from sequence) |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti VAV1 (pTyr174) antibody recognizes VAV1, also known as vav guanine nucleotide exchange factor 1 when phosphorylated at tyrosine 174. VAV1 is a member of the Vav family of guanine nucleotide exchange factors (GEFs). GEFs are involved in the activation of small GTPases which play a role in many signaling pathways. Potential substrates for VAV1 activity include Rac1, Cdc42 RhoA and RhoG. VAV1 is phosphorylated on tyrosine 174 leads to conformational changes and activation of VAV1 (Katzav 2015). |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding tyrosine 174 of human VAV1 |
Other Names | [VAV1 (pTyr174)], [VAV1; VAV1; VAV; VAV] |
Gene, Accession # | [VAV1], Gene ID: 7409, NCBI: P15498.4, UniProt: P15498 |
Catalog # | MBS225324 |
Price | $375 |
Order / More Info | VAV1 (pTyr174) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |