Human CEACAM6 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CEACAM6 |
| Clone | [9A6] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry, CELISA, ELISA (EIA), Western Blot (WB) and Immunohistology on cryosections |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: anti-human CEACAM6 (NCA; CD66c). Background: CEA-related cell adhesion molecule 6 (CEACAM6, NCA) belongs to the carcinoembryonic antigen (CEA) gene family (1,2). It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein with a Mr of 90,000 which is strongly expressed on epithelial cells of the fetal and adult gastrointestinal tract, epithelia of glandular tissues, squamous epithelial cell of the tongue, esophagus and cervix as well as on granulocytes (2,3). CEACAM6 expression is upregulated in many adenocarcinomas and leukemias. Like all members of the CEA family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constant-like A and B do |
| Immunogen | Immunogen: Immunogen: tumor cell lines expressing CEACAM6 |
| Other Names | [CD66c; NCA], [CEACAM6; CEACAM6; NCA; CEAL; CD66c; NCA] |
| Gene, Accession # | Gene ID: 4680, NCBI: NP_002474.4, UniProt: P40199 |
| Catalog # | MBS468045 |
| Price | $505 |
| Order / More Info | Human CEACAM6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zimmermann W (2002). Carcinoembryonic antigen. In Wiley Encyclopedia of Molecular Medicine(T. Creighton, ed.), John Wiley & Sons Inc., New York, USA, pp. 459-462.Hammarstrom S (1999). The carcinoembryonic antigen (CEA) family: structures, suggestedfunctions and expression in normal and malignant tissues. Semin Cancer Biol. 9, 67-81.Scholzel S, Zimmermann W, Schwarzkopf G, Grunert F, Rogaczewski B and Thompson J(2000). Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentiallyexpressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps andearly adenomas. Am J Pathol 156, 595-605.Grunert F, Stocks SC, Nagel G., Zimmermann W, Thompson JA, Jantscheff P and KromerB. (1996). CD66 family Workshop: Binding of myeloid blind panel antibodies and CD66Subsection antibodies to HeLa transfectants expressing individual CD66 molecules. In LeukocyteTyping VI: White cell Differentiation Antigens (T. Kishimoto et al., eds.), Garland Publishing Inc.,New York and London, pp. 1012-1025. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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