DOC2B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDOC2B
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, bovine
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionSpecificity: DOC2B Antibody detects endogenous levels of DOC2B. Description: Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes (By similarity).Subunit Structure: Interacts with the SNARE (soluble N-ethylmaleimide-sensitive factor
ImmunogenImmunogen: A synthesized peptide derived from human DOC2B. Tissue Specificity: Widely expressed with highest levels in brain and kidney. Expressed in pancreatic islet cells (at protein level).
Other Names[Doc2 beta; Doc2-beta; Doc2b; DOC2B_HUMAN; DOC2BL; Double C2 like domain containing protein beta; Double C2 like domains beta; Double C2 like domains beta like; Double C2-like domain-containing protein beta; OTTMUSP00000006522; RP23 78H4.2]
Gene, Accession #[DOC2B], Gene ID: 8447, NCBI: NP_003576.2, UniProt: Q14184
Catalog #MBS9611706
Price$240, $280
Order / More InfoDOC2B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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