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Antigenic Specificity | DOC2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DOC2B Antibody detects endogenous levels of DOC2B. Description: Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes (By similarity).Subunit Structure: Interacts with the SNARE (soluble N-ethylmaleimide-sensitive factor |
Immunogen | Immunogen: A synthesized peptide derived from human DOC2B. Tissue Specificity: Widely expressed with highest levels in brain and kidney. Expressed in pancreatic islet cells (at protein level). |
Other Names | [Doc2 beta; Doc2-beta; Doc2b; DOC2B_HUMAN; DOC2BL; Double C2 like domain containing protein beta; Double C2 like domains beta; Double C2 like domains beta like; Double C2-like domain-containing protein beta; OTTMUSP00000006522; RP23 78H4.2] |
Gene, Accession # | [DOC2B], Gene ID: 8447, NCBI: NP_003576.2, UniProt: Q14184 |
Catalog # | MBS9611706 |
Price | $240, $280 |
Order / More Info | DOC2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |