AQP11 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | AQP11 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit IgG polyclonal antibody for Aquaporin-11(AQP11) detection. Background: AQP11 has a unique asparagine-proline-alanine (NPA) box distinct from those of other AQPs, suggesting a different pore structure and function. Using Northern blot analysis, they detected highest expression of mouse Aqp11 in testis, followed by liver and kidney. Expression was much weaker in heart, brain, and muscle. Western blot analysis of mouse kidney membrane fractions detected Aqp11 at an apparent molecular mass of 26 kD, lower than the calculated molecular mass of 30 kD. Immunohistochemical analysis localized Aqp11 to mouse renal proximal tubule cells, where it showed a perinuclear distribution. Fluorescence-tagged Aqp11 localized with an endoplasmic reticulu |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human AQP11 (35-70aa ARQQLHRPVAHAFVLEFLATFQLCCCTHELQLLSEQ), different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids. |
| Other Names | [AQP11; AQP-11; AQP 11; Aquaporin11; Aquaporin-11; Aquaporin 11; Q8NBQ7], [AQP11; AQP11; AQPX1; AQPX1; AQP-11] |
| Gene, Accession # | [AQP11], Gene ID: 282679, NCBI: NP_766627.1, UniProt: Q8NBQ7 |
| Catalog # | MBS178800 |
| Price | $280 |
| Order / More Info | AQP11 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Morishita, Y., Matsuzaki, T., Hara-chikuma, M., Andoo, A., Shimono, M., Matsuki, A., Kobayashi, K., Ikeda, M., Yamamoto, T., Verkman, A., Kusano, E., Ookawara, S., Takata, K., Sasaki, S., Ishibashi, K.Disruption of aquaporin-11 produces polycystic kidneys following vacuolization of the proximal tubule. Molec. Cell. Biol. 25: 7770-7779, 2005. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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