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Antigenic Specificity | NXF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total NXF1 protein. Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export.Braun I.C., EMBO J. 18:1953-1965(1999).Kang Y., Genes Dev. 13:1126-1139(1999).Bear J., Mol. Cell. Biol. 19:6306-6317(1999). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from N-terminal of human NXF1. |
Other Names | [MEX67; TAP; Tip-associated protein; mRNA export factor TAP; nuclear RNA export factor 1] |
Gene, Accession # | [NXF1], Gene ID: 10482, NCBI: NP_001074960.1, UniProt: Q9UBU9 |
Catalog # | MBS9412240 |
Price | $200, $255 |
Order / More Info | NXF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |