SUR1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SUR1 |
| Clone | [S289-16] |
| Host Species | Mouse |
| Reactive Species | mouse, hamster, rat |
| Isotype | IgG1 |
| Format | PE-ATTO 594 conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects ~160kDa. Does not cross-react with SUR2B Scientific Background: Sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class of anti-diabetic drugs whose mechanism of action is to promote insulin release from pancreatic beta cells. More specifically, SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6.x (6.1 and 6.2) (1). The association of four Kir6.x and four SUR subunits form an ion conducting channel commonly referred to as the KATP channel. The primary function of the sulfonylurea receptor is to sense intracellular levels of the nucleotides ATP and ADP and in response facilitate the open or closing its associated Kir6.x potassium channel. |
| Immunogen | n/a |
| Other Names | [AM60008PU-N; ABC36; Abcc8; ATP binding cassette sub family C member 8; HHF1; HRINS; MRP8; PHHI; SUR; SUR1; Sulfonylurea receptor (hyperinsulinemia); ATP binding cassette sub family C (CFTR/MRP) member 8], [Abcc8; Abcc8; Sur; Sur1; Sur; Sur1] |
| Gene, Accession # | Gene ID: 25559, NCBI: NP_037171.2, UniProt: Q09429 |
| Catalog # | MBS800158 |
| Price | $445 |
| Order / More Info | SUR1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Campbell J.D., Sansom M.S., Ashcroft F.M. (2003) EMBO Resp. 4(11): 1038-1042. 2. Nichols C.G. (2006) Nature. 440 (7083): 470-476. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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