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Antigenic Specificity | CACNA1S |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | humanpredicted: porcine, bovine, rabbit, dog |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CACNA1S Antibody detects endogenous levels of CACNA1S. Description: Pore-forming, alpha-1S subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle via their interaction with RYR1, which triggers Ca2+ release from the sarcplasmic reticulum and ultimately results in muscle contraction. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group.Post Translational Modifications: The alpha-1S subunit is found in two isoforms in the skeletal muscle: a minor form of 212 kDa containing the complete amino acid sequence, and |
Immunogen | Immunogen: A synthesized peptide derived from human CACNA1S. Tissue Specificity: Skeletal muscle specific. |
Other Names | [alpha-1 polypeptide; CAC1S_HUMAN; CACH1; Cach1b; CACN1; CACNA1S; CACNL1A3; Calcium channel; Calcium channel, L type, alpha 1 polypeptide, isoform 3, skeletal; Calcium channel, L type, alpha 1 polypeptide, isoform 3, skeletal muscle; Calcium channel, L type, alpha 1 polypeptide, isoform 3, skeletal muscle, hypokalemic periodic paralysis; Calcium channel, skeletal muscle dihydropyridine sensitive, alpha 1 subunit; Calcium channel, voltage dependent, L type, alpha 1S subunit; Calcium channel, voltage-dependent, L type, alpha 1S subunit, b; Cav1.1; CCHL1A3; Dihydropyridine receptor; Dihydropyridine sensitive L type calcium channel alpha 1 subunit; fmd; HOKPP; HypoPP; isoform 3; L type; Malignant hyperthermia susceptibility 5; mdg; MHS5; ROB1; sj; skeletal muscle; TTPP1; Voltage gated calcium channel subunit alpha Cav1.1; Voltage-dependent L-type calcium channel subunit alpha-1S; Voltage-gated calcium channel subunit alpha Cav1.1] |
Gene, Accession # | [CACNA1S], Gene ID: 779, NCBI: NP_000060, UniProt: Q13698 |
Catalog # | MBS9611624 |
Price | $240, $280 |
Order / More Info | CACNA1S Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |