Edit |   |
---|---|
Antigenic Specificity | KDEL |
Clone | [10C3] |
Host Species | Mouse |
Reactive Species | avian, insect, mammalian, plant, yeast |
Isotype | IgG2a |
Format | Protein G purified |
Size | 0.05 mg, 0.2 mg, 1 mg |
Concentration | n/a |
Applications | ELISA, FC, ICC, IF, IHC (PS), Immunoprecipitation (IP), Western Blot (WB), Electron Microscopy (EM) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes proteins containing the KDEL sequence. The tetrapeptide KDEL, located at the carboxy-terminal sequences of luminal proteins, is a retrieval motif essential for the precise sorting of these proteins along the secretory pathway. KDEL proteins perform essential functions in the endoplasmic reticulum (ER) related to protein folding as well as assembly. The localization of chaperones and other soluble proteins to the ER is achieved by their continuous retrieval from post-ER compartments by the KDEL receptor (Erd2p), which is a membrane protein localized in the Golgi apparatus. |
Immunogen | Immunogen: Synthetic peptide corresponding to aa 649-654 (S649EKDEL654) of rat Grp78. |
Other Names | [Lys-Asp-Glu-Leu; Lysine-aspartic acid-glutamate-leucine], [Hspa5; Hspa5; BIP; GRP78; Grp78; GRP-78; BiP] |
Gene, Accession # | [KDEL], Gene ID: 25617, NCBI: P06761.1, UniProt: P06761 |
Catalog # | MBS565113 |
Price | $285, $535, $1870 |
Order / More Info | KDEL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |