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Antigenic Specificity | Human Cullin 1 / CUL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Cullin 1 Antibody detects endogenous levels of total Cullin 1 protein. Cullin-1 is a negative regulator of the cell cycle that controls the abundance of G1 cyclins during embryogenesis; Cul1 mutants produce abnormally small cells due to an accelerated progression of the cell cycle G1-to-S-phases and the absence of mitotic arrest phase. Null mutations cause hyperplasia of all tissues. Cul-1 is part of the SCF ubiquitin ligase complex with S KP1 and F box-containing protein. Cul-1 is homologous to the yeast cdc53 protein. |
Immunogen | Immunogen Description: Synthetic peptide from human Cullin 1 (aa727-776). |
Other Names | [Cullin 1 / CUL1 (aa727-776) IHC-plus; CUL1; Cullin 1; Cullin-1; CUL-1; Human Cullin 1; CUL1], [CUL1; CUL1; CUL-1] |
Gene, Accession # | [CUL1], Gene ID: 8454, NCBI: NP_003583.2, UniProt: Q13616 |
Catalog # | MBS247945 |
Price | $530 |
Order / More Info | Human Cullin 1 / CUL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |