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Antigenic Specificity | PDGFRL (N-term), 16-44 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: bovine, monkey) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PDGFRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-44 amino acids from the N-terminal region of human PDGFRL. This gene encodes a protein with significant sequencesimilarity to the ligand binding domain of platelet-derived growthfactor receptor beta. Mutations in this gene, or deletion of achromosomal segment containing this gene, are associated withsporadic hepatocellular carcinomas, colorectal cancers, andnon-small cell lung cancers. This suggests this gene product mayfunction as a tumor suppressor. |
Immunogen | n/a |
Other Names | [Platelet-derived growth factor receptor-like protein; PDGFR-like protein; PDGF receptor beta-like tumor suppressor; PDGFRL; PRLTS] |
Gene, Accession # | [PDGFRL], Gene ID: 5157, NCBI: NP_006198.1, UniProt: Q15198 |
Catalog # | MBS9213155 |
Price | $165, $370 |
Order / More Info | PDGFRL (N-term), 16-44 Antibody from MYBIOSOURCE INC. |
Product Specific References | Davila, S., et al. Genes Immun. 11(3):232-238(2010) Guo, F.J., et al. World J. Gastroenterol. 16(12):1465-1472(2010) Riker, A.I., et al. BMC Med Genomics 1, 13 (2008) : Xu, M., et al. BMC Genomics 9 SUPPL 1, S12 (2008) : Seitz, S., et al. Genes Chromosomes Cancer 45(6):612-627(2006) |