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Antigenic Specificity | Collagen VIII alpha2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Collagen VIII alpha2 antibody detects endogenous levels of total Collagen VIII alpha2. Function: Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity).Subunit Structure: Homotrimers, or heterotrimers in association with alpha 2(VIII) type collagens. Four homotrimers can form a tetrahedron stabilized by central interacting C-terminal NC1 trimers.Post-translational Modifications: |
Immunogen | Immunogen: A synthesized peptide derived from human Collagen VIII alpha2 Subcellular Location: Secreted; Extracellular Space; Extracellular Matrix; Basement Membrane. Tissue Specificity: Expressed primarily in the subendothelium of large blood vessels. Also expressed in arterioles and venules in muscle, heart, kidney, spleen, umbilical cord, liver and lung and is also found in connective tissue layers around hair follicles, around nerve bundles in muscle, in the dura of the optic nerve, in corne |
Other Names | [AI429819; Collagen, type VIII, alpha 2; FECD; FECD1; FLJ00201; MGC116970; MGC116972; MGC90765; PPCD; PPCD2; RP23-113P22.2; RP4-665N4.3] |
Gene, Accession # | [COL8A2], Gene ID: 1296, NCBI: NP_001281276.1, UniProt: P25067 |
Catalog # | MBS9609220 |
Price | $240, $280 |
Order / More Info | Collagen VIII alpha2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |