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Antigenic Specificity | CD71/Transferrin Receptor (TFRC) |
Clone | [66IG10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | CF488 conjugate |
Size | 0.5 mL |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer. |
Immunogen | Immunogen: Human thymocytes (T-cells) |
Other Names | [Mtvr-1; p90; TFR1; TFRC transferrin receptor (p90 CD71); TRFR] |
Gene, Accession # | [TFRC], Gene ID: 7037, NCBI: NP_001121620.1, UniProt: P02786 |
Catalog # | MBS4381284 |
Price | $340 |
Order / More Info | CD71/Transferrin Receptor (TFRC) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. K. Moolenaar et al. Cancer research 50,1102-1106, 1990. 2. Van de Rijna M, Geurts van Kessel AHM, Kroezen V, van Agthoven AJ, Verstijnen K, Terhorst C, Hilgers J: Cytogenet Cell Genet 1983;36:525-531. 3. Oudermans et al. Cancer, 1986; 58:1252 |