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Antigenic Specificity | Mouse Lck (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Lck antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 224-257 amino acids from the Central region of Mouse Lck. Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T- cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein to the vicinity of t |
Immunogen | n/a |
Other Names | [Purified Rabbit (Pab); Proto-oncogene tyrosine-protein kinase LCK; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell-specific protein-tyrosine kinase; p56-LCK; Lck; Lsk-t] |
Gene, Accession # | [Lck], Gene ID: 16818, NCBI: NP_001155905.1, UniProt: P06240 |
Catalog # | MBS9215711 |
Price | $150 |
Order / More Info | Mouse Lck (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Marth J.D.,et al.Cell 43:393-404(1985).Voronova A.F.,et al.Nature 319:682-685(1986).Carninci P.,et al.Science 309:1559-1563(2005).Garvin A.M.,et al.Mol. Cell. Biol. 8:3058-3064(1988).Voronova A.F.,et al.Mol. Cell. Biol. 7:4407-4413(1987). |