Human FSD2 / Frizzled 2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human FSD2 / Frizzled 2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | bovine, dog, hamster, horse, human, mouse, porcine, rat. predicted reactivity: rabbit, sheep (at least 90% immunogen sequence identity) |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.05 mg |
| Concentration | 1 mg/ml |
| Applications | Immunohistochemistry (IHC - Paraffin) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human Frizzled 2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FZD7 (67%), OR1A2 (56%), NFATC2 (50%). FZD2 is a Frizzled Receptor that mediates Wnt signaling, which is required for proper axis development in the embryo. FZD2 is developmentally regulated. Studies of rat FZD2 indicate that the protein signals through a calcium-releasing pathway and that FDZ2 expression modulates protein kinase C (PKC) localization and stimulates PKC activity in vitro. Increased levels of FZD2 mRNA have been observed in primary gastric cancer and in head and neck squamous carcinoma and gastric cancer cell lines. |
| Immunogen | Immunogen Description: Synthetic 18 amino acid peptide from 3rd extracellular domain of human Frizzled 2. Percent identity with other species by BLAST analysis: Human, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Horse, Pig (100%); Sheep, Rabbit (94%); Opossum (89%). |
| Other Names | [FSD2 / Frizzled 2 (Extracellular Domain) IHC-plus; Dfrizzled2; Fz2; Frizzled family receptor 2; Frizzled-2; HFz2; Frizzled homolog 2; Fz-2; FzE2; Mfz10; Rfz2; Frizzled 2; Human FSD2; Frizzled 2], [FSD2] |
| Gene, Accession # | [FZD2], Gene ID: 2535, NCBI: NP_001457.1, UniProt: Q14332 |
| Catalog # | MBS244087 |
| Price | $530 |
| Order / More Info | Human FSD2 / Frizzled 2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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