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Antigenic Specificity | UBE2D1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total UBE2D1 protein. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-ac |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human UBE2D1. |
Other Names | [SFT; UBCH5; UBC4/5; UBCH5A; E2(17)KB1] |
Gene, Accession # | [UBE2D1], Gene ID: 7321, NCBI: NP_003329.1, UniProt: P51668 |
Catalog # | MBS9403097 |
Price | $255 |
Order / More Info | UBE2D1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |