NEDD4L Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNEDD4L
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration2.8 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total NEDD4L protein. This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension.
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
Other Names[RSP5; NEDD4-2; NEDD4.2; hNEDD4-2]
Gene, Accession #[NEDD4L], Gene ID: 23327, NCBI: NP_001138436.1, UniProt: Q96PU5
Catalog #MBS9407823
Price$255
Order / More InfoNEDD4L Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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