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Antigenic Specificity | NEDD4L |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 2.8 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total NEDD4L protein. This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Fusion protein corresponding to residues near the C terminal of human neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
Other Names | [RSP5; NEDD4-2; NEDD4.2; hNEDD4-2] |
Gene, Accession # | [NEDD4L], Gene ID: 23327, NCBI: NP_001138436.1, UniProt: Q96PU5 |
Catalog # | MBS9407823 |
Price | $255 |
Order / More Info | NEDD4L Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |