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Antigenic Specificity | PNMT |
Clone | [AT1C11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, k |
Format | Protein G purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phenylethanolamine N-methyltransferase (PNMT) catalyzes the synthesis of epinephrine and plays an important role in regulating cardiovascular function. Expression of PNMT is regulated by hormonal and neural stimuli because its promoter contains sequences responding to cholinergic and depolarization stimuli. PNMT is the final enzyme in the catecholamine pathway, catalyzing the conversion of norepinephrine to epinephrine using as the cosubstrate and methyl donor, S-adenosylmethionine. |
Immunogen | Immunogen: Recombinant human PNMT (1-282aa) purified from E. coli |
Other Names | [Phenylethanolamine N-methyltransferase; PENT; PNMTase; Noradrenaline-N-methyltransferase; Phenylethanolamine N-methyltransferase], [PNMT; PENT; PNMTase] |
Gene, Accession # | [PNMT], Gene ID: 5409, NCBI: NP_002677, UniProt: P11086 |
Catalog # | MBS200216 |
Price | $240, $315 |
Order / More Info | PNMT Antibody from MYBIOSOURCE INC. |
Product Specific References | Wurtman R.J., et al. (1965) Science 150: 1464-1465; Wurtman R.J., et al. (1966) J Biol Chem 241: 2301-2305; Huang C., et al. (2011) lAmerican Journal of Hypertension 24: 1222-1226; |