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Antigenic Specificity | FAM59A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FAM59A Antibody: FAM59A, also known as GAREM, was initially identified through a mass spectroscoptic method that measures different phosphotyrosine states of proteins in response to different cell stimuli. FAM59A is a downstream molecule in the EGF signaling pathway that is tyrosine-phosphorylated, and this phosphorylation is needed for the binding of Grb2, an adaptor protein crucial to the transduction of growth signals from the plasma membrane to the nucleus. ERK activation in response to EGF stimulation is regulated by FAM59A in COS-7 and HeLa cells, and the overexpression of FAM59A stimulated cell proliferation and colony formation in soft agar, suggesting that FAM59A might be a critical protein with roles in ligand-mediated signaling p |
Immunogen | Immunogen: FAM59A antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human FAM59A. Buffer: FAM59A Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [FAM59A; Gm944; FAM59A; C18orf11; GRB2-associated and regulator of MAPK protein; GRB2-associated and regulator of MAPK1; family with sequence similarity 59, member A], [GAREM; GAREM; Gm944; FAM59A; C18orf11; C18orf11; FAM59A] |
Gene, Accession # | [FAM59A], Gene ID: 64762, NCBI: Q9H706.2, UniProt: Q9H706 |
Catalog # | MBS150293 |
Price | $375 |
Order / More Info | FAM59A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |