Edit |   |
---|---|
Antigenic Specificity | ZNHIT3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1.9mg/mL |
Applications | Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ZNHIT3 (zinc finger, HIT-type containing 3), also known as TRIP3 (thyroid receptor-interacting protein 3) or HNF-4a coactivator, is a 155 amino acid protein that contains one HIT-type zinc finger and regulates PPAR(c)-mediated adipocyte differentiation. ZNHIT3 also coactivates HNF-4a, and as a thyroid receptor interacting protein, ZNHIT3 interacts with the ligand binding domain of the thyroid receptor. The gene encoding ZNHIT3 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1, 200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is di |
Immunogen | Immunogen: Synthetic peptide of human ZNHIT3 |
Other Names | [HNF 4a coactivator; Thyroid hormone receptor interactor 3; Thyroid receptor interacting protein 3; TR interacting protein 3; TRIP 3; TRIP3; Zinc finger HIT domain containing protein 3; Zinc finger HIT type 3; Zinc finger, HIT domain containing 3; Zinc finger, HIT type containing 3] |
Gene, Accession # | [ZNHIT3], Gene ID: 9326, NCBI: NP_001268361.1, UniProt: Q15649 |
Catalog # | MBS2561447 |
Price | $110, $150, $225 |
Order / More Info | ZNHIT3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |