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Antigenic Specificity | Angiotensin I Converting Enzyme (ACE)/CD143 |
Clone | [9B9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length |
Immunogen | Immunogen: Full-length recombinant human ACE/CD143 protein |
Other Names | [ACE; ACE1; angiotensin 1 converting enzyme 1; carboxycathepsin; CD143; CD143 antigen; DCP; DCP1; dipeptidyl carboxypeptidase 1; Kininase II; MVCD3; peptidase P; testicular ECA] |
Gene, Accession # | [ACE], Gene ID: 1636, NCBI: ABA39229.1, UniProt: P12821 |
Catalog # | MBS4380833 |
Price | $190, $340, $340 |
Order / More Info | Angiotensin I Converting Enzyme (ACE)/CD143 Antibody from MYBIOSOURCE INC. |
Product Specific References | Morell NW et al. Cardiovasc Res. 1997 May;34(2):393-403. |