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Antigenic Specificity | Mad 4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Mad 4 Polyclonal Antibody detects endogenous levels of Mad 4 protein. MXD4 is a member of the MAD gene family. The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human Mad 4 at AA rangle: 10-90 |
Other Names | [Rabbit Mad 4; MXD4; BHLHC12; Max dimerization protein 4; Max dimerizer 4; Class C basic helix-loop-helix protein 12; bHLHc12; Max-associated protein 4; Max-interacting transcriptional repressor MAD4] |
Gene, Accession # | [MAD4], Gene ID: 10608, NCBI: NP_006445.1, UniProt: Q14582 |
Catalog # | MBS9704163 |
Price | $130, $220, $325 |
Order / More Info | Mad 4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |