Human xCT (N-TERMINAL) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human xCT (N-TERMINAL) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.05 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Immunohistology Paraffin* |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti human xCT (N-terminal) antibody detects an epitope within the N-terminal (NT) of the cysteine/glutamate transporter xCT, which forms a complex with the 4F2 heavy chain (CD98), via a disulfide bond. This heterodimer forms a Na+ independent amino acid transport system which leads to the uptake of extracellular L-cystine in conjunction to L-glutamate efflux. This system is thought to play an important role in the protection of neurons and activated macrophages against oxidative stress. xCT is the receptor which mediates Kaposi's sarcoma herpesvirus (KSHV) cell fusion. |
| Immunogen | Histology Positive Control Tissue: Neurons or astrocytes Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human xCT were raised by repeated immunisations of rabbit with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
| Other Names | [cystine/glutamate transporter; Cystine/glutamate transporter; cystine/glutamate transporter; amino acid transport system xc-; calcium channel blocker resistance protein CCBR1; solute carrier family 7 member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Solute carrier family 7 member 11; xCT], [SLC7A11; SLC7A11; xCT; CCBR1] |
| Gene, Accession # | [xCT], Gene ID: 23657, NCBI: NP_055146.1, UniProt: Q9UPY5 |
| Catalog # | MBS221510 |
| Price | $550 |
| Order / More Info | Human xCT (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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