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Antigenic Specificity | SRF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total SRF protein. This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human serum response factor (c-fos serum response element-binding transcription factor) |
Other Names | [MCM1] |
Gene, Accession # | [SRF], Gene ID: 6722, NCBI: NP_001278930.1, UniProt: P11831 |
Catalog # | MBS9410141 |
Price | $255 |
Order / More Info | SRF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |