Bag3 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Bag3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 3(BAG3) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: BAG family molecular chaperone regulator 3(BAG3) is a member of a conserved family of cyto-protective proteins that bind to and regulate Hsp70 family molecular chaperones. BAG3 mutations are responsible for familial dilated cardiomyopathy. BAG3 polymorphisms are also associated with sporadic forms of the disease together with HSPB7 locus. In muscle cells, BAG3 cooperates with the molecular chaperones Hsc70 and HspB8 to induce the degradation of mechanically damaged cytoskeleton components in lysosomes. This process is called chaperone-assisted selective autophagy(CASA) and is ess |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Bag3 (491-506aa LEKLEQKAIDVPGQVQ), identical to the related mouse and rat sequences. |
| Other Names | [BAG family molecular chaperone regulator 3; BCL2-associated athanogene 3; BAG 3; BAG family molecular chaperone regulator 3; BAG-3; Bag3; BAG3_HUMAN; Bcl 2 binding protein; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; BCL2 associated athanogene 3; BCL2 binding athanogene 3; BIS; Docking protein CAIR 1; Docking protein CAIR-1], [BAG3; BAG3; BIS; MFM6; BAG-3; CAIR-1; BIS; BAG-3] |
| Gene, Accession # | [BAG3], Gene ID: 9531, NCBI: O95817.3, UniProt: O95817 |
| Catalog # | MBS176324 |
| Price | $315 |
| Order / More Info | Bag3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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