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Antigenic Specificity | PDGFRA |
Clone | [2C11F11] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. |
Immunogen | Immunogen: Purified recombinant fragment of human PDGFRA (AA: 361-528) expressed in E. Coli. |
Other Names | [CD140A; PDGFR2; PDGFR-2; RHEPDGFRA] |
Gene, Accession # | [PDGFRA], Gene ID: 5156, NCBI: NP_006197.1, UniProt: P16234 |
Catalog # | MBS8539405 |
Price | $280 |
Order / More Info | PDGFRA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |