APP-Y756, 735-763 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | APP-Y756, 735-763 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: monkey, mouse, porcine, rat) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.467 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This APP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 735-763 amino acids from human APP. APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). |
| Immunogen | n/a |
| Other Names | [Amyloid beta A4 protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II; N-APP; Soluble APP-alpha; S-APP-alpha; Soluble APP-beta; S-APP-beta; C99; Beta-amyloid protein 42; Beta-APP42; Beta-amyloid protein 40; Beta-APP40; C83; P3(42); P3(40); C80; Gamma-secretase C-terminal fragment 59; Amyloid intracellular domain 59; AICD-59; AID(59); Gamma-CTF(59); Gamma-secretase C-terminal fragment 57; Amyloid intracellular domain 57; AICD-57; AID(57); Gamma-CTF(57); Gamma-secretase C-terminal fragment 50; Amyloid intracellular domain 50; AICD-50; AID(50); Gamma-CTF(50); C31; APP; A4; AD1] |
| Gene, Accession # | [APP], Gene ID: 351, NCBI: NP_000475.1, UniProt: P05067 |
| Catalog # | MBS9209531 |
| Price | $165, $370 |
| Order / More Info | APP-Y756, 735-763 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Blomqvist, M.E., et al., Neurobiol. Aging 26(6):795-802 (2005). Yoon, I.S., et al., J. Biol. Chem. 280(20):20140-20147 (2005). Chen, M., et al., Biochem. Biophys. Res. Commun. 330(3):714-721 (2005). Yamamoto, M., et al., Am. J. Pathol. 166(5):1475-1485 (2005). Moir, R.D., et al., J. Biol. Chem. 280(17):17458-17463 (2005). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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