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Antigenic Specificity | GDF5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total GDF5 polyclonal antibody. Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 (By similarity). Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. |
Immunogen | Immunogen: Recombinant Human Growth/differentiation factor 5 protein(202-501aa) |
Other Names | [Growth/differentiation factor 5; GDF-5; Bone morphogenetic protein 14; BMP-14; Cartilage-derived morphogenetic protein 1; CDMP-1; Lipopolysaccharide-associated protein 4; LAP-4; LPS-associated protein 4; GDF5; BMP14; CDMP1] |
Gene, Accession # | [GDF5], Gene ID: 8200, NCBI: NP_000548.2, UniProt: P43026 |
Catalog # | MBS9415256 |
Price | $320 |
Order / More Info | GDF5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |