CHD7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCHD7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionSpecificity: Multiple isoforms of CHD7 are known to exist. CHD proteins belong to a superfamily of proteins of ATP-dependent chromatin remodeling enzymes that have a unique combination of functional domains, including two N-terminal chromodomains, a SNF2-like ATPase/helicase domain and a DNA-binding domain. These proteins are thought to play a role in early embryonic development by affecting chromatin structure and gene expression. Mutations in one member of this family, CHD7, result in CHARGE syndrome. It colocalizes with embryonic stem (ES) cell master regulators OCT4/POU5F1, SOX2, and NANOG and is thought to modulate ES-specific gene transcription. Together with SOX2, CHD7 has been suggested to also regulate several human disease genes.
ImmunogenImmunogen Type: Peptide Immunogen Description: Raised against an 18 amino acid peptide near the amino terminus of human CHD7.
Other Names[Chromodomain helicase DNA binding protein 7, IS3, KAL5]
Gene, Accession #[CHD7], Gene ID: 55636, NCBI: NP_060250.2, UniProt: Q9P2D1
Catalog #MBS9403345
Price$320
Order / More InfoCHD7 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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