ME2 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | ME2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ME2 antibody is human specific. At least two isoforms of ME2 are known to exist; this antibody will detect both isoforms. ME2 antibody is predicted not to cross-react with ME1. ME2 is a homotetrameric, mitochondrial NAD-dependent malic enzyme that catalyzes the oxidative decarboxylation of malate to pyruvate (1). It is related to malic enzyme 1 (ME1), a cytoplasmic NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis (2). The expression of both malic enzymes is reciprocally regulated by p53; this regulation has been shown to modulate metabolism and senescence (3). Certain single-nucleotide polymorphism haplotypes of the ME2 gene have been shown to increase the risk for idiopathic generalized epilepsy (4). |
| Immunogen | Immunogen: ME2 antibody was raised against a 17 amino acid peptide near the center of human ME2. Buffer: ME2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [ME2; ODS1; NAD-dependent malic enzyme; mitochondrial; Malic enzyme 2; NAD-ME; malic enzyme 2, NAD(+)-dependent, mitochondrial], [ME2; ME2; ODS1; NAD-ME] |
| Gene, Accession # | [ME2], Gene ID: 4200, NCBI: NP_002387, UniProt: P23368 |
| Catalog # | MBS153703 |
| Price | $375 |
| Order / More Info | ME2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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