CD44 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CD44 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD44 is a type I transmembrane glycoprotein that mediates cellcell and cellmatrix interaction through its affinity for hyaluronic acid (HA) and possibly through other parts of the extracellular matrix (ECM). CD44 is highly polymorphic, possesses a number of alternative splice variants and undergoes extensive posttranslational modifications (1,2). Increased surface levels of CD44 are characteristic of T cell activation, and expression of the protein is upregulated during the inflammatory response. Interactions between CD44 and HER2 have been linked to an increase in ovarian carcinoma cell growth (1-3). CD44 interacts with ezrin, radixin and moesin (ERM), linking the actin cytoskeleton to the plasma membrane and the ECM (4-6). CD44 is constit |
| Immunogen | Immunogen: A synthetic -peptide of human CD44 |
| Other Names | [CD44; CD44; CDW44; CSPG8; ECMR-III; HCELL; IN; LHR; MC56; MDU2; MDU3; MGC10468; MIC4; MUTCH-I; Pgp1], [CD44; CD44; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III; LHR; MDU2; MDU3; MIC4; ECMR-III; PGP-1; PGP-I] |
| Gene, Accession # | Gene ID: 960, NCBI: NP_000601.3, UniProt: P16070 |
| Catalog # | MBS125562 |
| Price | $200, $275, $430 |
| Order / More Info | CD44 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Goodison, S. et al. (1999) Mol. Pathol. 52, 189-196. 2. Cichy, J. and Pure, E. (2003) J. Cell Biol. 161, 839-843. 3. Bourguignon, L.Y. et al. (1997) J. Biol. Chem. 272, 27913-27918. 4. Legg, J.W. et al. (2002) Nat. Cell Biol. 4, 399-407. 5. Yonemura, S. et al. (1998) J. Cell Biol. 140, 885-895. 6. Tsukita, S. et al. (1994) J. Cell Biol. 126, 391-401. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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